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Begin Chemo and/or Radiation

Patients usually receive chemotherapy and/or radiation before the transplant, which prepares the body to receive new cells. There are a few different types of regimens, and your care team will decide which one is best for you.

Different types of regimens:

  • Myeloablative (high intensity) -- uses strong doses of chemotherapy to remove of all bone marrow cells
  • Reduced-intensity (RIC) -- uses lower doses that are less toxic, often for older or medically fragile patients
  • Non-myeloablative -- minimal intensity, relying more on the donor's immune system to provide a new immune system.

What Is Chemotherapy? It is given before the stem cells to prepare the bone marrow for the new cells. Why It Matters:

  • Eliminate diseased/cancer cells
  • Eliminates immune system cells
  • It makes room for new stem cells to grow
  • It reduces the risk of transplant rejection

💡Chemo Prep Tips

Ask your team what side effects to expect and how to manage them (next step has more info)

Stay hydrated and eat what you can---nutritional support is available

Bring comfort items for long infusion days (books, music, snacks)

Use a calendar or app to track medications and appointments

💡Infection Prevention Tips

Wash hands frequently and avoid crowds

Wear a mask if recommended by your team

Keep your central line clean and follow care instructions

Report any fever, chills, or signs of infection immediately

🩺Questions to Ask Your Care Team

Bring these to your next appointment

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What type of preparative regimen will I receive?

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How does it compare to what other patients receive?

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What are the short- and long-term side effects?

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What should I expect during chemotherapy or radiation?

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How can I prepare emotionally and physically?

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What support is available for my caregiver?

📋Mental Health Servies/Support Services

Recovery after transplant is complex---and you don't have to navigate it alone.

These support services are designed to meet emotional, physical, spiritual, and practical needs for both patients and families.

WhoServices Provided
Social WorkHelp with housing, insurance, and caregiver support
Mental HealthCounseling for patients and families
Child Life / SchoolSupport for kids and school transitions
Physical TherapyHelp with strength, movement, and recovery
Home Health CareNursing support at home
Pain / Palliative CareComfort and symptom management
ChaplainSpiritual care and emotional support
Pet TherapyVisits from trained therapy animals
Financial ServicesHelp with billing, insurance, and aid programs

Talk with your provider about which support services may be right for you. Everyone's recovery is different, and your care team can help match you with resources that fit your needs---whether it's emotional support, physical therapy, school planning, or home care.

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