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Infections and infection prevention

After a stem cell transplant, the immune system is significantly weakened, making infection prevention a critical part of recovery. Patients are vulnerable to bacterial, viral, and fungal infections, especially in the first months after transplant. Staying informed and proactive can help reduce risk and improve outcomes.

Common Infection Risks

  • Bacterial infections -- often related to central lines, skin, or gastrointestinal tract
  • Viral infections -- can be from virus you have already been exposed in the past such as CMV, EBV, HSV, Varicella, or spread from other people such as the flu
  • Fungal infections -- usually from environment that everyone is exposed to but only those with weak immune system cannot fight

Your care team may prescribe antibiotics, antifungals, and antivirals as part of your prevention plan. These medications are essential even if you feel well.

💡Prevention Strategies

Practice strict personal hygiene---frequent handwashing, clean linens, and mouth care

Follow safe food handling---ask your provider for specific recommendations

Take environmental precautions---avoid construction zones, fresh soil, standing water, and live plants

Use protective measures---masking in public, avoiding crowds, and limiting visitors

Maintain central line care---follow dressing change protocols and report any redness or swelling

💡Tips

If you notice any symptoms, call your care team---don't wait

Avoid crowded areas, especially during flu season or outbreaks

Be cautious with visitors---ask about recent illness or exposures

Let restaurants or public spaces know about your immune status if needed

Stay consistent with masking and distancing, even if others aren't

🩺Questions to Ask Your Care Team

Bring these to your next appointment

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What infection control measures does my center follow?

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What are my current restrictions---food, pets, public spaces?

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Are there guidelines for masking or distancing at home and in public?

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Can I have pets, and if so, what precautions should I take?

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What symptoms should I report immediately?

💬What I Wish I'd Known

From families who've been there

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Which foods are safe, and which should be avoided.

Ask Dietitian

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Whether tap water, well water, or bottled water is recommended

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If houseplants or gardening pose a risk

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How sexual activity may be affected---ask about timing, protection, and hygiene

That central line care is part of infection prevention---ask for training and supplies

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